Select the incorrect statement with reference to Rh grouping.

A. Erythroblastosis foetalis is a condition observed having foetus with $ ext{Rh}^{-ve}$ blood and mother with $ ext{Rh}^{+ve}$ blood.

B. Rh antigen is observed on RBCs in the majority of human beings.

C. Before blood transfusion, Rh group should also be matched.

D. Rh incompatibility is observed when a pregnant mother is $ ext{Rh}^{-ve}$ and the foetus is $ ext{Rh}^{+ve}$.

E. Erythroblastosis foetalis can be avoided by administering anti-Rh antibodies to the mother immediately after the delivery of the second child.

Choose the answer from the options given below :

Question

Select the incorrect statement with reference to Rh grouping.

A. Erythroblastosis foetalis is a condition observed having foetus with $	ext{Rh}^{-ve}$ blood and mother with $	ext{Rh}^{+ve}$ blood.

B. Rh antigen is observed on RBCs in the majority of human beings.

C. Before blood transfusion, Rh group should also be matched.

D. Rh incompatibility is observed when a pregnant mother is $	ext{Rh}^{-ve}$ and the foetus is $	ext{Rh}^{+ve}$.

E. Erythroblastosis foetalis can be avoided by administering anti-Rh antibodies to the mother immediately after the delivery of the second child.

Choose the answer from the options given below :

Accepted Answer

C. 1. **Checking statement A**: **erythroblastosis foetalis** actually occurs when the **mother is Rh-negative** and the **foetus is Rh-positive** — statement A wrongly reverses this (says foetus is Rh-negative and mother is Rh-positive), so **A is incorrect**.

2. **Checking statement B**: the **Rh antigen** is indeed present on the RBCs of the majority (nearly 80%) of humans, so **B is correct**.

3. **Checking statement C**: it is true that before any blood transfusion, the **Rh group must also be matched**, in addition to the ABO group, to avoid destruction of red blood cells, so **C is correct**.

4. **Checking statement D**: Rh incompatibility genuinely occurs when a **pregnant mother is Rh-negative and the foetus is Rh-positive**, so **D is correct**.

5. **Checking statement E**: to prevent erythroblastosis foetalis in future pregnancies, anti-Rh antibodies must be administered to the mother immediately after the delivery of the **first** child, not the second child as stated — so **E is incorrect**.

6. Since statements A and E are the incorrect ones, hence the correct answer is **C: A and E only**.